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Why ivermectin should not be used to treat or prevent Covid-19

Taking large doses of this drug is dangerous and can cause serious harm.

US Food and Drug Administration
3 minute read
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Covid-19. We’ve been living with it for what sometimes seems like forever. Given the number of deaths that have occurred from the disease, it’s perhaps not surprising that some consumers are looking at unconventional treatments, not approved or authorised by the Food and Drug Administration (FDA).

Though this is understandable, please beware. The FDA’s job is to carefully evaluate the scientific data on a drug to be sure that it is both safe and effective for a particular use, and then to decide whether or not to approve it. Using any treatment for Covid-19 that’s not approved or authorised by the FDA, unless part of a clinical trial, can cause serious harm.

There seems to be a growing interest in a drug called ivermectin to treat humans with Covid-19. Ivermectin is often used in the US to treat or prevent parasites in animals. The FDA has received multiple reports of patients who have required medical support and been hospitalised after self-medicating with ivermectin intended for horses.

Here’s what you need to know about ivermectin

FDA has not approved ivermectin for use in treating or preventing Covid-19 in humans. Ivermectin tablets are approved at very specific doses for some parasitic worms, and there are topical (on the skin) formulations for head lice and skin conditions like rosacea. Ivermectin is not an anti-viral (a drug for treating viruses).

Taking large doses of this drug is dangerous and can cause serious harm.

If you have a prescription for ivermectin for an FDA-approved use, get it from a legitimate source and take it exactly as prescribed.

Never use medications intended for animals on yourself. Ivermectin preparations for animals are very different from those approved for humans.

What is ivermectin and how is it used?

Ivermectin tablets are approved by the FDA to treat people with intestinal strongyloidiasis and onchocerciasis, two conditions caused by parasitic worms. In addition, some topical (on the skin) forms of ivermectin are approved to treat external parasites like head lice and for skin conditions such as rosacea.

Some forms of ivermectin are used in animals to prevent heartworm disease and certain internal and external parasites. It’s important to note that these products are different from the ones for people, and safe when used as prescribed for animals, only.

When can taking ivermectin be unsafe?

The FDA has not reviewed data to support use of ivermectin in Covid-19 patients to treat or to prevent Covid-19; however, some initial research is underway. Taking a drug for an unapproved use can be very dangerous. This is true of ivermectin, too.

There’s a lot of misinformation around, and you may have heard that it’s okay to take large doses of ivermectin. That is wrong.

Even the levels of ivermectin for approved uses can interact with other medications, like blood-thinners. You can also overdose on ivermectin, which can cause nausea, vomiting, diarrhoea, hypotension (low blood pressure), allergic reactions (itching and hives), dizziness, ataxia (problems with balance), seizures, coma and even death.

Ivermectin products for animals are different from ivermectin products for people

For one thing, animal drugs are often highly concentrated because they are used for large animals like horses and cows, which can weigh a lot more than we do – a tonne or more. Such high doses can be highly toxic in humans.

Moreover, FDA reviews drugs not just for safety and effectiveness of the active ingredients, but also for the inactive ingredients. Many inactive ingredients found in animal products aren’t evaluated for use in people. Or they are included in much greater quantity than those used in people. In some cases, we don’t know how those inactive ingredients will affect how ivermectin is absorbed in the human body.

Meanwhile, effective ways to limit the spread of Covid-19 continue to be to wear your mask, stay at least six feet from others who don’t live with you, wash hands frequently, and avoid crowds.

The views expressed in this article are those of the author(s) and do not necessarily reflect the position of MalaysiaNow.